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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7887f84addb02804f058f5be34e8f741e2a406c20b0988d127c7b812b4ebb5cf' 
  AND token = 'sp+e1+ZCajbcCU//P9ATuqa22fPY/jakUQMLO4AaKoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}