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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a378b941ce3b0342df3ea00f2a50180e938ef0b059a4b827a0a4dc38c3a22b8d' 
  AND token = 'J/D6bf4yiN02kyPfeHCogaYga883lSz86lwHUd2boaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}