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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60cd53e98ceec8ab63ef4517e15b047e4454c9801ddcb696b7ed0a3a5254d866' 
  AND token = '9Qi1wl4nHQyffBFGAOwIkRWifkBjDe50Tx9My6zhVaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}