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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '405341598e6df33ca18b50096faf00f7c3faf2ba6591375f2047becfb2b90276' 
  AND token = '0PO4A3C1YJ3MMDtryNxA881JQVsdZayhEqeYz2PM/gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}