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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d17c833a47654745e2d3aaad5dce7c94bc0821ea3271b2316007df0a27f07e8' 
  AND token = 'lJgKoZnYhnTmd7B+cW365PXEg6+QjvWrzsFhBjQa1QI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}