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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e108d85e6a54c50bb6f7538e525eb84a9b02742b2eec457c8c70c50ecf141e05' 
  AND token = '2aDZ2SrEiu1FsRO2BJrngeWoNjfr6gCJn8LEzMdgmWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}