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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ef43c1eb66fae093b84befd88ccd05f49da5c9f33ba5edd9b9b7bcb4a8d2ac1' 
  AND token = '42Z3XXp2OKmrgBNFwsXoGsS5fRgJG79ST1yuogPPqhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}