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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25c649ee1c145bf0631577dd4590ccb8115202a22341bdbb1f633f18dfd3d88e' 
  AND token = 'orWHoizMa0HbCChavi4l3sR4KKzSSDjM2JFia9aIvYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}