SELECT 
  cscart_product_prices.product_id, 
  MIN(
    IF(
      cscart_product_prices.percentage_discount = 0, 
      cscart_product_prices.price, 
      cscart_product_prices.price - (
        cscart_product_prices.price * cscart_product_prices.percentage_discount
      )/ 100
    )
  ) AS price 
FROM 
  cscart_product_prices 
WHERE 
  cscart_product_prices.product_id IN (
    3489, 3798, 3927, 4781, 5045, 2720, 3281, 
    3335, 2194, 2223, 2321, 2734, 3369, 
    3336, 3407, 3807, 4162, 4592, 2386, 
    2392, 2786, 3364, 3954, 8266
  ) 
  AND cscart_product_prices.lower_limit = 1 
  AND cscart_product_prices.usergroup_id IN (0, 1) 
GROUP BY 
  cscart_product_prices.product_id

Query time 0.00094

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "16.81"
    },
    "grouping_operation": {
      "using_filesort": false,
      "table": {
        "table_name": "cscart_product_prices",
        "access_type": "range",
        "possible_keys": [
          "usergroup",
          "product_id",
          "lower_limit",
          "usergroup_id"
        ],
        "key": "product_id",
        "used_key_parts": [
          "product_id"
        ],
        "key_length": "3",
        "rows_examined_per_scan": 24,
        "rows_produced_per_join": 4,
        "filtered": "19.99",
        "index_condition": "(`softwarepirmam_hewadelivard_cscart_4`.`cscart_product_prices`.`product_id` in (3489,3798,3927,4781,5045,2720,3281,3335,2194,2223,2321,2734,3369,3336,3407,3807,4162,4592,2386,2392,2786,3364,3954,8266))",
        "cost_info": {
          "read_cost": "16.33",
          "eval_cost": "0.48",
          "prefix_cost": "16.81",
          "data_read_per_join": "115"
        },
        "used_columns": [
          "product_id",
          "price",
          "percentage_discount",
          "lower_limit",
          "usergroup_id"
        ],
        "attached_condition": "((`softwarepirmam_hewadelivard_cscart_4`.`cscart_product_prices`.`lower_limit` = 1) and (`softwarepirmam_hewadelivard_cscart_4`.`cscart_product_prices`.`usergroup_id` in (0,1)))"
      }
    }
  }
}

Result

product_id price
2194 35000.00000000
2223 38000.00000000
2321 477000.00000000
2386 65000.00000000
2392 74000.00000000
2720 18000.00000000
2734 23000.00000000
2786 270000.00000000
3281 135000.00000000
3335 6550000.00000000
3336 7100000.00000000
3364 80000.00000000
3369 44000.00000000
3407 30000.00000000
3489 5999000.00000000
3798 5000.00000000
3807 11000.00000000
3927 30000.00000000
3954 72000.00000000
4162 875000.00000000
4592 240000.00000000
4781 162000.00000000
5045 256000.00000000
8266 1080000.00000000