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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41e5452e217dfe79e505b3abc01884b63bac9bc81d1e173805507bc5cfe42e90' 
  AND token = 'PS9cDnZTtbZbwxzbTfnFfksTFdKvME9Ndjz99LqoOrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}