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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c94a9627bea954dfe15f93b85f5c559447e1dee13a5248f9a124ce9b21045bcf' 
  AND token = 'F5zx/peOEdO3+gTHydmjFWc4y4542yO+ladhWCyG6yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}