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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7270e5dcd4e4dcd4d5c5b373832b82c28d529154141626cdc1e6e6421e8b3231' 
  AND token = 'LCdll5x0Q/LoVXw8QEPubDJvhxAyIQGfMwWXbwOfS0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}