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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bde21c404aedd9d85d7b93db9bedfd57dbcff42af939a3db2d3f909f428442a4' 
  AND token = 'JFs8de+kg7GxhpVDbfcMFDF0YofAjYljIQCh8PNQbQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}