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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '376cd7c8df3a3be5458d08e26ce0f69c61f93ddc163fc75bf9512450b9727387' 
  AND token = '1WTfFwbWod+1i4BSuIEQHELAFWiHH6JhE+4DlRj+Uu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}