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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43e585021a0c8c71ed653ea3ac57e342c123f280792894af9adfe366e84a0611' 
  AND token = 'b7iqNSH5OV6kOpfvol9wV4t53PDme81Y/ywgCtfRHlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}