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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1df17794261f81a4f7a53a771820e556692684244f2316126e72d12426b7e728' 
  AND token = 'l6S+v5mIeu/JyYvMhpbEC9AV9xjMxuvER5aPtgX5Vnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}