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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7eb3867db3e1bb214515ef13ff869d8aa57ca5b6227315631c378d4caa67cff9' 
  AND token = 'SRJO5rqRUEHtMs003/d+8WiZZbvwxynjfW3ex0TRQtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}