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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d5fc35a1f80aeaaca7d247b63460dd9cea66c3df24988410666976d60808659' 
  AND token = 'Tu5vaCL7UzobVFcrCyaXJCGoOG7Z3IwCVKfiQE1s06M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}