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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43c0a60ddd3545a79d67bd6bc9324944f3925616dd115754d997d5ea27d50ef4' 
  AND token = 'o/ADNC0dMjPxg4gr6uwC2vuJ9QoYxxbkAzy37E2xj4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}