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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10c250c1d305a2a2e1a1daa01cd4131f018f184e6ab41f4826a24741e28170f5' 
  AND token = 'sTK//CLiBERQ+RrYFT6GGS70lmj4Ij5Cqge8jYKezQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}