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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21b016e7ba9d8f54db576abbcd93a7c5a5ffe0879864da65575da07455b57a78' 
  AND token = 'HKpJgIy9nduop5hoTmNV2ztPD5ST+FTap8YaeN8bsAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}