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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a8902758c74f8f0d01f0ae4c012e5b19d39fb7fe8da2265e317389fe3e446cc' 
  AND token = 'XO1azYHDp0/s3RQg06Sjo0ODy0pTBx/6xKmz/powBik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00094

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}