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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0426eebe49b7747301741429ccc80c066d0c0d055e317bc595034df9c4e351c0' 
  AND token = 'Cl5Cwn1+IuObjyYtEU4bCQZDDTzc0fM/Vse1rsv8P3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}