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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16564ee2e34cf4b46c212e1d121a19abe872a16c866cc35e34630acbb5a21628' 
  AND token = 'uHj9dpaYWhgoqwqLuOa4kTXoDNeGFvlAuqgkKrB27Hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}