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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4e8110a78a8ba3e9f3aefb1f444cdd9f862d0e2ce0e6a082db3aacf34c348b8' 
  AND token = 'nKibQr+VfpjBiPNXq6xRD9C7Ke3GYVD8XbQH2svqYj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}