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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7534b464443c4e69913debf5995d3e24bbecea78dfcf1e18b01d0b231497e24c' 
  AND token = 'e+9O6bEiAHV2GZF9yv5Pd0kSZm+BFBFnJjwxJ6DBDFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}