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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4954c86739c9a86281b0f6ea7ebc748f2c30dfac1c40ba7c331d33d92290d234' 
  AND token = 'G6Ybz2dGMr0Ky9TQGD44pSleq66Eto1jKyTICzbECuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}