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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e2f93a6f6c6844abc9e57e6bb14f376c489283c85b8f9c5a1a6c1576fb8fa43' 
  AND token = 'Ka5PBNotk/TgBwidiMn+FVKe8DkV+e2lt+RL+ClRx7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}