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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21c0f34a22f831dd0be5d41485724d547207d3398627ee20a9e83091aa55cb44' 
  AND token = 'mB09zdb02aNpDhNTdhnC8D6KHzHnRtEv3OomnQumq+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}