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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10546e73dafbfe27fc3675106c4fec45629ff4ec8834f729084bad5fdf1b67af' 
  AND token = 'ilrt6EemwJN+SEFJGs59VO/Rej0Sc20Q+Wgbku5qMHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}