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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c44d00b58cae442989f457fd3b6ae314866c9e7a9451617ce1a6bd0f1cb82994' 
  AND token = 'IPZ2+KtzorrPUnNgpvMIbM+wFaVgRhcr8egPQOPdqRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}