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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8bca003953d2636b5dc8d95e0a734ace5c1f3f78a130daabf244bf36c835704' 
  AND token = 'CdBT23R78A9phRmNx0D0s2682vYjNAptQjnRRlbOp1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}