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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8c1e0d71b3a6d670dc776e31b9ed07904eb6783d92f90f42a7e9d9423da9681' 
  AND token = 'Q9Yb/cATGZgSYEoC986Tu3Lw6204cxqgzDjlTa4oHUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}