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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64eb90c0e44e3f491feea3dbafef425de26a14fa2832b4353721c59f6adac4f0' 
  AND token = '5nbQxv9a4HEc+Z66AiglnbqDIzT1Kqbqh6aSyFPqOi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}