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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '327a1516614a11f8f4c4b5b1eefdd5a1e1331395a2b8e00daa41284009249d7c' 
  AND token = 'QNR/R1X4jZDLeMgT+ddMDkaHROpFcTagGKZJm49XX2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}