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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '059d7bebd26ea02cb1fa45681fd0e3631affd922f3064e9f74136c45661632af' 
  AND token = 'dVvQGOTCze8EN9xt3rCOG2oYoiB+tbQ0ATL53EMOXkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}