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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b303b49e8ee74338731aece9650596ef4058d02ee0a2b60586a38865f27d3222' 
  AND token = 'bSbEL2bCTN0ycIG9tUyjNHjhcSbM0bqfBFMBk3jDWJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}