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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2db59f2fd162c23553629a27ee5cec9905fa304df04e3ab6d8df27a56b2d6b4c' 
  AND token = 'KH295qjfnOSOKy+hIzzi15kdXyfp23vZauRrbJqW1MQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00082

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}