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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05a0f9993faffbbb3b8cf1757b59c82b590e2f0d95c6fb63df202214c0a72442' 
  AND token = 'ABIs7HoDzGW0fXNo9X+xnHpN2/GWn4m6dZXKtWDUspo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}