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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '158c652e625d8a679e75896db0608d1330d597ed5dde49db6f932035fd7675ab' 
  AND token = 'rNV8ITuRbbnqALwNrevvUbG4qoFRluM18jfsZA/yoo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}