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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d7e01984673d6403fe85ad94abe8362e547dfdc42c906f92a621ec303f29019' 
  AND token = 'sUB67+q1ysYoI2/1/cEYJUiwhJJQG7WpPO5zE36PW7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}