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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21ee158959c33c9769c6c51b6813abea30b71b5737ecc9379515f097a709c192' 
  AND token = '5TN5WBw/yXK/mqu5xv1twxQoZYQRLvNBlbLHaOh2M+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}