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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e19e5200a5f4a6012614495e89777a896fc7dcf03acfcb88d2c355c3e02af22' 
  AND token = 'Q5MW776Y9eD3yvD9u8uv38i6D7Pk/QrGY6f8UFc2nb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}