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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57a36caa6ce5d09cde3ad7717683df4011bae588b6af1f72f8c3a2062d5e0c64' 
  AND token = 'shwyTIxz276ZjRfgA02mHutJhRm+sOgxRAXbNnuZuWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}