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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '324196f8ea476dc06dce02b5d8dead7f391e80c8aa43ac2e53566759e01f325e' 
  AND token = 'WhFcr51ufPwH2e1NFYcYkjpN0QqYLpNyap87N627cHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}