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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b527869f61b5d5b173d736dce995aa51fe299aeff8a3b9ed90eaeb05a51729e3' 
  AND token = 'HYdpG6bN2OYiVc5pykUAcHjI/dxl9seV9kmC+aaoD50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}