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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fa609016d656e100f5433f47d28cd6d65f6b0b5928d5efbc6600ed2b7cb6645' 
  AND token = 'HGIEHkdctduIaAKVpjb39xNm8Ht4lguV7pd0uzVS41M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}