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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cab2cf448436533fcb92d5a0ec85ad620ad41b0f619580d24921034d8d182a21' 
  AND token = 'jcY/D0kX8hh9BPiXU5qztXWle4QerUZzPkRbRFy2+As=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}