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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecd02f35b67eb1e3ae53de1a138d3a7a185053b0f15aaabb14257de64baed501' 
  AND token = 'a+JdTn7RGhvQyo5B7DfAW5Ua7GUJmgZSsRQQZqEFG48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}