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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b7265c1b9a445fe1674ae34e9e893e69bc3ef19e040d11e29ea898594445e53' 
  AND token = 'IMUNTjmuYF2wOcATlzvOy9hPMAD7Fccl2oPLAoU/c5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}